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Regulatory Actions of Toll-Like Receptor 2 (TLR2) and TLR4 in Leishmania donovani Infection in the Liver

In livers of susceptible but self-curing C57BL/6 mice, intracellular Leishmania donovani infection enhanced Toll-like receptor 4 (TLR4) and TLR2 gene expression. In the liver, infected TLR4(−/−) mice showed reduced gamma interferon (IFN-γ), tumor necrosis factor (TNF), and inducible nitric oxide syn...

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Main Authors: Murray, Henry W., Zhang, Yunhua, Zhang, Yan, Raman, Vanitha S., Reed, Steven G., Ma, Xiaojing
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697629/
https://ncbi.nlm.nih.gov/pubmed/23589575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01468-12
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