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Rho Kinase Regulates Induction of T-Cell Immune Dysfunction in Abdominal Sepsis

T-cell dysfunction increases susceptibility to infections in patients with sepsis. In the present study, we hypothesized that Rho kinase signaling might regulate induction of T-cell dysfunction in abdominal sepsis. Male C57BL/6 mice were treated with the specific Rho kinase inhibitor Y-27632 (5 mg/k...

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Detalhes bibliográficos
Main Authors: Hasan, Z., Palani, K., Zhang, S., Lepsenyi, M., Hwaiz, R., Rahman, M., Syk, I., Jeppsson, B., Thorlacius, Henrik
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697588/
https://ncbi.nlm.nih.gov/pubmed/23630965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00126-13
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