Multiplex Liquid Chromatography-Tandem Mass Spectrometry Assay for Simultaneous Therapeutic Drug Monitoring of Ribavirin, Boceprevir, and Telaprevir

New directly acting antivirals (DAAs) that inhibit hepatitis C virus (HCV) replication are increasingly used for the treatment of chronic hepatitis C. A marked pharmacokinetic variability and a high potential for drug-drug interactions between DAAs and numerous drug classes have been identified. In...

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Autors principals: Aouri, Manel, Moradpour, Darius, Cavassini, Matthias, Mercier, Thomas, Buclin, Thierry, Csajka, Chantal, Telenti, Amalio, Rauch, Andri, Decosterd, Laurent A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2013
Matèries:
Antiviral Agents
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697367/
https://ncbi.nlm.nih.gov/pubmed/23629707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00281-13
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