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Polyphosphate Deficiency in Mycobacterium tuberculosis Is Associated with Enhanced Drug Susceptibility and Impaired Growth in Guinea Pigs

Inorganic polyphosphate (polyP), a linear polymer of hundreds of phosphate residues linked by ATP-like phosphoanhydride bonds, is found in all organisms and performs a wide variety of functions. This study shows that polyP accumulation occurs in Mycobacterium tuberculosis upon exposure to various st...

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Autors principals: Singh, Ramandeep, Singh, Mamta, Arora, Garima, Kumar, Santosh, Tiwari, Prabhakar, Kidwai, Saqib
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697247/
https://ncbi.nlm.nih.gov/pubmed/23585537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00038-13
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