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Sensitivity of a mutator gene in Chinese hamster ovary cell to deoxynucleoside triphosphate pool alterations.
The Thy- mutants of Chinese hamster ovary cells have a 5- to 10-fold elevated pool of deoxycytidine 5'-triphosphate (dCTP) and are auxotrophic for thymidine as an apparent consequence of a single mutation. thy is also a mutator gene, elevating the spontaneous rate of mutation 5- to 200-fold for...
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
1981
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| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC369712/ https://ncbi.nlm.nih.gov/pubmed/9279378 |
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