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Sensitivity of a mutator gene in Chinese hamster ovary cell to deoxynucleoside triphosphate pool alterations.

The Thy- mutants of Chinese hamster ovary cells have a 5- to 10-fold elevated pool of deoxycytidine 5'-triphosphate (dCTP) and are auxotrophic for thymidine as an apparent consequence of a single mutation. thy is also a mutator gene, elevating the spontaneous rate of mutation 5- to 200-fold for...

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Bibliografiset tiedot
Julkaisussa:Mol Cell Biol
Päätekijä: Meuth, M
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Taylor & Francis 1981
Aiheet:
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369712/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9279378/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.1.7.652
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