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Dexamethasone promotes tolerance in vivo by enriching CD11c(lo)CD40(lo) tolerogenic macrophages

We previously showed that antigen immunization in the presence of the immunosuppressant dexamethasone (a strategy we termed “suppressed immunization”) could tolerize established recall responses of T cells. However, the mechanism by which dexamethasone acts as a tolerogenic adjuvant has remained unc...

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Detalhes bibliográficos
Main Authors: Zheng, Guoxing, Zhong, Shibo, Geng, Yajun, Munirathinam, Gnanasekar, Cha, Isaac, Reardon, Catherine, Getz, Godfrey S., van Rooijen, Nico, Kang, Youmin, Wang, Bin, Chen, Aoshuang
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697049/
https://ncbi.nlm.nih.gov/pubmed/23001956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201242468
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