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Nitro aspirin (NCX4040) induces apoptosis in PC3 metastatic prostate cancer cells via hydrogen peroxide (H(2)O(2))-mediated oxidative stress

Non-steroidal anti-inflammatory drugs (NSAID) have shown promise as anticancer agents by inducing cell death apart from their antipyretic, anti-inflammatory and anti-thrombogenic effects. In our current study, we investigated the oxidative stress mediated cell death mechanism of a NSAID derivative N...

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Detalhes bibliográficos
Publicado no:Free Radic Biol Med
Main Authors: Chinnapaka, Somaiah, Zheng, Guoxing, Chen, Aoshuang, Munirathinam, Gnanasekar
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6848783/
https://ncbi.nlm.nih.gov/pubmed/31446057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2019.08.025
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