Alterations in the DNA Methylation Patterns of Calca, Timp3, Mmp2, and Igf2r are Associated with Chronic Cystitis in a Cyclophosphamide-induced Mouse Model

OBJECTIVES: To determine whether epigenetic changes occurred during cyclophosphamide (CYP)-induced chronic bladder inflammation in mice. Epigenetics plays a role in the regulation of inflammatory genes in non-cancer diseases such as asthma and COPD. However, epigenetic (DNA methylation) changes duri...

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Main Authors: Choi, In-Seon, Yu, Kevin, Kim, Jayoung, De Guzman, Erika, Weisenberger, Daniel J., Oghamian, Shirley, Kim, Hee Ju, Lee, Kyung Hwa, Carroll, Cindy, Trinh, Binh N., Kim, Myungjin, Houshdaran, Sahar, Laird, Peter W., Jones, Peter A., Warburton, David, Koh, Chester J.
Format: Artigo
Language:Inglês
Published: 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697025/
https://ncbi.nlm.nih.gov/pubmed/23806407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.urology.2013.04.010
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