Fetal Brain-directed AAV Gene Therapy Results in Rapid, Robust, and Persistent Transduction of Mouse Choroid Plexus Epithelia

Fetal brain-directed gene addition represents an under-appreciated tool for investigating novel therapeutic approaches in animal models of central nervous system diseases with early prenatal onset. Choroid plexuses (CPs) are specialized neuroectoderm-derived structures that project into the brain�...

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Hlavní autoři: Haddad, Marie Reine, Donsante, Anthony, Zerfas, Patricia, Kaler, Stephen G
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2013
Témata:
Methods - Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696907/
https://ncbi.nlm.nih.gov/pubmed/23799375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2013.27
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