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Increasing brain serotonin corrects CO(2) chemosensitivity in methyl-CpG-binding protein 2 (Mecp2)-deficient mice
Mice deficient in the transcription factor methyl-CpG-binding protein 2 (Mecp2), a mouse model of Rett syndrome, display reduced CO(2) chemosensitivity, which may contribute to their breathing abnormalities. In addition, patients with Rett syndrome and male mice that are null for Mecp2 show reduced...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3696880/ https://ncbi.nlm.nih.gov/pubmed/23180809 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/expphysiol.2012.069872 |
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