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Orientation-specific responses to sustained uniaxial stretching in focal adhesion growth and turnover

Cells are mechanosensitive to extracellular matrix (ECM) deformation, which can be caused by muscle contraction or changes in hydrostatic pressure. Focal adhesions (FAs) mediate the linkage between the cell and the ECM and initiate mechanically stimulated signaling events. We developed a stretching...

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Bibliografiske detaljer
Main Authors: Chen, Yun, Pasapera, Ana M., Koretsky, Alan P., Waterman, Clare M.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696741/
https://ncbi.nlm.nih.gov/pubmed/23754369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1221637110
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