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Fast and accurate genotype imputation in genome-wide association studies through pre-phasing
Sequencing efforts, including the 1000 Genomes Project and disease-specific efforts, are producing large collections of haplotypes that can be used for genotype imputation in genome-wide association studies (GWAS). Imputing from these reference panels can help identify new risk alleles, but the use...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3696580/ https://ncbi.nlm.nih.gov/pubmed/22820512 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.2354 |
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