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A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies

Genotype imputation methods are now being widely used in the analysis of genome-wide association studies. Most imputation analyses to date have used the HapMap as a reference dataset, but new reference panels (such as controls genotyped on multiple SNP chips and densely typed samples from the 1,000...

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Bibliographische Detailangaben
Hauptverfasser: Howie, Bryan N., Donnelly, Peter, Marchini, Jonathan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689936/
https://ncbi.nlm.nih.gov/pubmed/19543373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000529
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