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CpG-depleted adeno-associated virus vectors evade immune detection
Due to their efficient transduction potential, adeno-associated virus (AAV) vectors are leading candidates for gene therapy in skeletal muscle diseases. However, immune responses toward the vector or transgene product have been observed in preclinical and clinical studies. TLR9 has been implicated i...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3696560/ https://ncbi.nlm.nih.gov/pubmed/23778142 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI68205 |
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