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Plant cysteine proteases that evoke itch activate protease-activated receptors

BACKGROUND: Bromelain, ficin and papain are cysteine proteases from plants that produce itch upon injection into skin. Their mechanism of action has not been considered previously. OBJECTIVES: To determine the mechanism by which these proteases function. METHODS: The ability of these proteases to ac...

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Bibliographic Details
Main Authors: Reddy, V.B., Lerner, E.A.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696472/
https://ncbi.nlm.nih.gov/pubmed/20491769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2133.2010.09862.x
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