Cerebrospinal Fluid Biomarkers and Proximity to Diagnosis in Preclinical Familial Alzheimer's Disease

BACKGROUND/AIMS: Biological markers of utility in tracking Alzheimer's disease (AD) during the presymptomatic prodromal phase are important for prevention studies. Changes in cerebrospinal fluid (CSF) levels of 42-amino-acid β-amyloid (Aβ(42)), total tau protein (t-tau) and phosphorylated tau a...

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Detalhes bibliográficos
Main Authors: Ringman, John M., Coppola, Giovanni, Elashoff, David, Rodriguez-Agudelo, Yaneth, Medina, Luis D., Gylys, Karen, Cummings, Jeffrey L., Cole, Greg M.
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2012
Assuntos:
Original Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696356/
https://ncbi.nlm.nih.gov/pubmed/22343824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000335729
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