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Conformation-Dependent Oligomers in Cerebrospinal Fluid of Presymptomatic Familial Alzheimer's Disease Mutation Carriers

BACKGROUND/AIMS: Oligomerization of amyloid beta (Aβ) is a hypothesized step in the formation of plaques in Alzheimer's disease (AD) but has been difficult to demonstrate in vivo in humans. As persons destined to develop familial AD (FAD) due to fully penetrant autosomal dominant mutations are...

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Bibliografiset tiedot
Päätekijät: Ringman, John M., Tomic, Jennifer L., Coppola, Giovanni, Elashoff, David, Gylys, Karen H., Glabe, Charles G.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: S. Karger AG 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3551434/
https://ncbi.nlm.nih.gov/pubmed/23341831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000345771
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