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Association of Genetic Variants in the Neurotrophic Receptor–Encoding Gene NTRK2 and a Lifetime History of Suicide Attempts in Depressed Patients

CONTEXT: A consistent body of evidence supports a role of reduced neurotrophic signaling in the pathophysiology of major depressive disorder (MDD) and suicidal behavior. Especially in suicide victims, lower postmortem brain messenger RNA and protein levels of neurotrophins and their receptors have b...

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Autors principals: Kohli, Martin A., Salyakina, Daria, Pfennig, Andrea, Lucae, Susanne, Horstmann, Sonja, Menke, Andreas, Kloiber, Stefan, Hennings, Johannes, Bradley, Bekh B., Ressler, Kerry J., Uhr, Manfred, Müller-Myhsok, Bertram, Holsboer, Florian, Binder, Elisabeth B.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696349/
https://ncbi.nlm.nih.gov/pubmed/20124106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/archgenpsychiatry.2009.201
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