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Smooth muscle relaxation and activation of the large conductance Ca(++) – activated K(+) (BK(Ca)) channel by novel oestrogens
BACKGROUND AND PURPOSE: Oestrogens can interact directly with membrane receptors and channels and can activate vascular BK(Ca) channels. We hypothesized that novel oestrogen derivatives could relax smooth muscle by an extracllular effect on the α and β(1) subunits of the BK(Ca) channel, rather than...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Blackwell Publishing Ltd
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3696336/ https://ncbi.nlm.nih.gov/pubmed/23586466 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12211 |
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