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Effects of vildagliptin versus sitagliptin, on cardiac function, heart rate variability and mitochondrial function in obese insulin-resistant rats

BACKGROUND AND PURPOSE: Long-term high-fat diet (HFD) consumption has been shown to cause insulin resistance, which is characterized by hyperinsulinaemia with metabolic inflexibility. Insulin resistance is associated with cardiac sympathovagal imbalance, cardiac dysfunction and cardiac mitochondrial...

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Detalhes bibliográficos
Main Authors: Apaijai, Nattayaporn, Pintana, Hiranya, Chattipakorn, Siriporn C, Chattipakorn, Nipon
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696328/
https://ncbi.nlm.nih.gov/pubmed/23488656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12176
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