Effects of vildagliptin versus sitagliptin, on cardiac function, heart rate variability and mitochondrial function in obese insulin-resistant rats

BACKGROUND AND PURPOSE: Long-term high-fat diet (HFD) consumption has been shown to cause insulin resistance, which is characterized by hyperinsulinaemia with metabolic inflexibility. Insulin resistance is associated with cardiac sympathovagal imbalance, cardiac dysfunction and cardiac mitochondrial...

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Autori principali: Apaijai, Nattayaporn, Pintana, Hiranya, Chattipakorn, Siriporn C, Chattipakorn, Nipon
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 2013
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Research Papers
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696328/
https://ncbi.nlm.nih.gov/pubmed/23488656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12176
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