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Effects of SH2 and SH3 deletions on the functional activities of wild-type and transforming variants of c-Src.

The amino-termina, noncatalytic half of Src contains two domains, designated the Src homology 2 (SH2) and Src homology 3 (SH3) domains, that are highly conserved among members of the Src family of tyrosine kinases. The SH2 domain (which can be further divided into the B and C homology boxes) and the...

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Publicat a:Mol Cell Biol
Autors principals: Seidel-Dugan, C, Meyer, B E, Thomas, S M, Brugge, J S
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1992
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369627/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1549129/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.4.1835-1845.1992
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