Complex intrachromosomal rearrangement in the process of amplification of the L-myc gene in small-cell lung cancer.

The L-myc gene was first isolated from a human small-cell lung cancer (SCLC) cell line on the basis of its amplification and sequence similarity to c-myc and N-myc. A new mechanism of L-myc activation which results from the production of rlf-L-myc fusion protein was recently reported. On the basis o...

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Main Authors: Sekido, Y, Takahashi, T, Mäkelä, T P, Obata, Y, Ueda, R, Hida, T, Hibi, K, Shimokata, K, Alitalo, K
Format: Artigo
Jezik:Inglês
Izdano: 1992
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC369618/
https://ncbi.nlm.nih.gov/pubmed/1312669
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