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Modulation of oxidative stability of haemoglobin inside liposome-encapsulated haemoglobin

The major hurdle in the formulation of liposome-encapsulated haemoglobin (LEH) is the oxidation of haemoglobin (Hb) into methaemoglobin during storage and after administration. In order to reduce this oxidative degradation, we tested various reducing conditions in the presence of catalase. We found...

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Main Authors: Awasthi, Vibhudutta, Yadav, Vivek R, Goins, Beth, Phillips, William T
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696053/
https://ncbi.nlm.nih.gov/pubmed/23231644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/02652048.2012.752535
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