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Nanovesicular Liposome-Encapsulated Hemoglobin (LEH) Prevents Multi-organ Injuries in a Rat Model of Hemorrhagic Shock

The goals of resuscitation in hemorrhagic shock are to correct oxygen deficit and to maintain perfusion pressure to the vital organs. We created liposome-encapsulated hemoglobin (LEH) as a nanoparticulate oxygen carrier (216 ± 2 nm) containing 7.2 g/dL hemoglobin, and examined its ability to prevent...

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Detalhes bibliográficos
Publicado no:Eur J Pharm Sci
Main Authors: Yadav, Vivek R, Rao, Geeta, Houson, Hailey, Hedrick, Andria, Awasthi, Shanjana, Roberts, Pamela R., Awasthi, Vibhudutta
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035221/
https://ncbi.nlm.nih.gov/pubmed/27503458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejps.2016.08.010
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