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Absence of α4 but not β2 integrins restrains development of chronic allergic asthma using mouse genetic models
OBJECTIVE: Chronic asthma is characterized by ongoing recruitment of inflammatory cells and airway hyperresponsiveness leading to structural airway remodeling. Although α4β1 and β2 integrins regulate leukocyte migration in inflammatory diseases and play decisive roles in acute asthma, their role has...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3696022/ https://ncbi.nlm.nih.gov/pubmed/19463772 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2009.03.010 |
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