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Prion Peptide Uptake in Microglial Cells – The Effect of Naturally Occurring Autoantibodies against Prion Protein

In prion disease, a profound microglial activation that precedes neurodegeneration has been observed in the CNS. It is still not fully elucidated whether microglial activation has beneficial effects in terms of prion clearance or whether microglial cells have a mainly detrimental function through th...

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書誌詳細
主要な著者: Roettger, Yvonne, Zerr, Inga, Dodel, Richard, Bach, Jan-Philipp
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3695867/
https://ncbi.nlm.nih.gov/pubmed/23840767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067743
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