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Prion Peptide Uptake in Microglial Cells – The Effect of Naturally Occurring Autoantibodies against Prion Protein

In prion disease, a profound microglial activation that precedes neurodegeneration has been observed in the CNS. It is still not fully elucidated whether microglial activation has beneficial effects in terms of prion clearance or whether microglial cells have a mainly detrimental function through th...

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Detalhes bibliográficos
Main Authors: Roettger, Yvonne, Zerr, Inga, Dodel, Richard, Bach, Jan-Philipp
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3695867/
https://ncbi.nlm.nih.gov/pubmed/23840767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067743
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