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All-trans retinoic acid attenuates airway inflammation by inhibiting Th2 and Th17 response in experimental allergic asthma

BACKGROUND: Airway inflammation is mainly mediated by T helper 2 cells (Th2) that characteristically produce interleukin (IL)-4, IL-5, and IL-13. Epidemiological studies have revealed an inverse association between the dietary intake of vitamin A and the occurrence of asthma. Serum vitamin A concent...

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Detalhes bibliográficos
Main Authors: Wu, Jinhong, Zhang, Yanjie, Liu, Qi, Zhong, Wenwei, Xia, Zhenwei
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3695807/
https://ncbi.nlm.nih.gov/pubmed/23800145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2172-14-28
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