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Live-virus exposure of vaccine-protected macaques alters the anti-HIV-1 antibody repertoire in the absence of viremia

BACKGROUND: We addressed the question whether live-virus challenges could alter vaccine-induced antibody (Ab) responses in vaccinated rhesus macaques (RMs) that completely resisted repeated exposures to R5-tropic simian-human immunodeficiency viruses encoding heterologous HIV clade C envelopes (SHIV...

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Autors principals: Bachler, Barbara C, Humbert, Michael, Lakhashe, Samir K, Rasmussen, Robert A, Ruprecht, Ruth M
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3695773/
https://ncbi.nlm.nih.gov/pubmed/23800339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-10-63
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