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Human p53 and CDC2Hs genes combine to inhibit the proliferation of Saccharomyces cerevisiae.
Human wild-type and mutant p53 genes were expressed under the control of a galactose-inducible promoter in Saccharomyces cerevisiae. The growth rate of the yeast was reduced in cells expressing wild-type p53, whereas cells transformed with mutant p53 genes derived from human tumors were less affecte...
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| Publicado no: | Mol Cell Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
1992
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369569/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1545817/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.3.1357 |
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