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Human p53 and CDC2Hs genes combine to inhibit the proliferation of Saccharomyces cerevisiae.

Human wild-type and mutant p53 genes were expressed under the control of a galactose-inducible promoter in Saccharomyces cerevisiae. The growth rate of the yeast was reduced in cells expressing wild-type p53, whereas cells transformed with mutant p53 genes derived from human tumors were less affecte...

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Publicat a:Mol Cell Biol
Autors principals: Nigro, J M, Sikorski, R, Reed, S I, Vogelstein, B
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1992
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369569/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1545817/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.3.1357
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