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Visualizing GroEL/ES in the Act of Encapsulating a Folding Protein
The GroEL/ES chaperonin system is required for the assisted folding of many proteins. How these substrate proteins are encapsulated within the GroEL-GroES cavity is poorly understood. Using symmetry-free, single-particle electron cryo-microscopy, we have characterized a chemically modified mutant of...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3695626/ https://ncbi.nlm.nih.gov/pubmed/23746846 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.04.052 |
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