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The HeLa Pur factor binds single-stranded DNA at a specific element conserved in gene flanking regions and origins of DNA replication.

A major site of DNA bending is located 1.6 kb upstream of the P1 transcription start site of the human c-myc gene, near the center of a reported zone of initiation of DNA replication. A repeated, purine-rich element, termed PUR, at the bend site is specifically bound by a protein in HeLa cell nuclea...

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Détails bibliographiques
Publié dans:Mol Cell Biol
Auteurs principaux: Bergemann, A D, Johnson, E M
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 1992
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369558/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1545807/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.3.1257
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