Nonsense codons in human beta-globin mRNA result in the production of mRNA degradation products.

Human beta zero-thalassemic beta-globin genes harboring either a frameshift or a nonsense mutation that results in the premature termination of beta-globin mRNA translation have been previously introduced into the germ line of mice (S.-K. Lim, J.J. Mullins, C.-M. Chen, K. Gross, and L.E. Maquat, EMB...

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Bibliografische gegevens

Gepubliceerd in:	Mol Cell Biol
Hoofdauteurs:	Lim, S K, Sigmund, C D, Gross, K W, Maquat, L E
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Taylor & Francis 1992
Onderwerpen:	Research Article
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369546/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1545796/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.3.1149-1161.1992
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