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The HIP1 binding site is required for growth regulation of the dihydrofolate reductase gene promoter.

The transcription rate of the dihydrofolate reductase (DHFR) gene increases at the G1/S boundary of the proliferative cell cycle. Through analysis of transiently and stably transfected NIH 3T3 cells, we have now demonstrated that DHFR promoter sequences extending from -270 to +20 are sufficient to c...

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Publicat a:Mol Cell Biol
Autors principals: Means, A L, Slansky, J E, McMahon, S L, Knuth, M W, Farnham, P J
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1992
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369537/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1545788/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.3.1054-1063.1992
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