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Alteration of a cyclic AMP-dependent protein kinase phosphorylation site in the c-Fos protein augments its transforming potential.

We have studied the phosphorylation of the nuclear oncoprotein Fos by cyclic AMP-dependent protein kinase (PKA). We demonstrate that the human c-Fos protein, phosphorylated either in vitro with purified PKA or in vivo in JEG3 cells following treatment with forskolin, has similar phosphotryptic pepti...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Cell Biol
Prif Awduron: Tratner, I, Ofir, R, Verma, I M
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Taylor & Francis 1992
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369532/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1545828/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.3.998
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