Bending of Adenovirus Origin DNA by Nuclear Factor I as Shown by Scanning Force Microscopy Is Required for Optimal DNA Replication

Nuclear factor I (NFI) is a transcription factor that binds to the adenovirus type 5 (Ad5) origin of replication and recruits the adenovirus DNA polymerase, thereby stimulating initiation of DNA replication in vitro. Using scanning force microscopy, we demonstrate that NFI induces a 60° bend upon bi...

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Publicat a:J Virol
Autors principals: Mysiak, Monika E., Bleijenberg, Marjoleine H., Wyman, Claire, Holthuizen, P. Elly, van der Vliet, Peter C.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2004
Matèries:
Replication
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369512/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14747557/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.4.1928-1935.2004
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