E-cadherin determines Caveolin-1 tumor suppression or metastasis enhancing function in melanoma cells

The role of caveolin-1 (CAV1) in cancer is highly controversial. CAV1 suppresses genes that favor tumor development, yet also promotes focal adhesion turnover and migration of metastatic cells. How these contrasting observations relate to CAV1 function in vivo is unclear. Our previous studies implic...

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Main Authors: Lobos-González, L, Aguilar, L, Diaz, J, Diaz, N, Urra, H, Torres, V, Silva, V, Fitzpatrick, C, Lladser, A, Hoek, K.S., Leyton, L, Quest, AFG
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3695072/
https://ncbi.nlm.nih.gov/pubmed/23470013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/pcmr.12085
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