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Wild-Type Mitochondrial DNA Copy Number in Urinary Cells as a Useful Marker for Diagnosing Severity of the Mitochondrial Diseases

The genotype-phenotype relationship in diseases with mtDNA point mutations is still elusive. The maintenance of wild-type mtDNA copy number is essential to the normal mitochondrial oxidative function. This study examined the relationship between mtDNA copy number in blood and urine and disease sever...

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Detalhes bibliográficos
Main Authors: Liu, Hui, Ma, Yinan, Fang, Fang, Zhang, Ying, Zou, Liping, Yang, Yanling, Zhu, Sainan, Wang, Songtao, Zheng, Xuefei, Pei, Pei, Li, Lin, Wu, Hairong, Xiao, Yang, Xu, Yufeng, Wang, Liwen, Cao, Yanyan, Pan, Hong, Qi, Yu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3695014/
https://ncbi.nlm.nih.gov/pubmed/23826218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067146
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