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Regulation of Thrombospondin-1 expression in alternatively activated macrophages and adipocytes: role of cellular crosstalk and omega-3 fatty acids

Thrombospondin-1 (TSP-1) expression in human adipose positively correlates with body mass index and may contribute to adipose dysfunction by activating TGF-β and/or inhibiting angiogenesis. Our objective was to determine how TSP-1 is regulated in adipocytes and polarized macrophages using a cocultur...

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Detalhes bibliográficos
Main Authors: Finlin, Brian S., Zhu, Beibei, Starnes, Catherine P., McGehee, Robert E., Peterson, Charlotte A., Kern, Philip A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3695002/
https://ncbi.nlm.nih.gov/pubmed/23528972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jnutbio.2013.01.007
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