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Muscle inflammatory response and insulin resistance: synergistic interaction between macrophages and fatty acids leads to impaired insulin action

Obesity is characterized by adipose tissue expansion as well as macrophage infiltration of adipose tissue. This results in an increase in circulating inflammatory cytokines and nonesterified fatty acids, factors that cause skeletal muscle insulin resistance. Whether obesity also results in skeletal...

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Detalhes bibliográficos
Main Authors: Varma, Vijayalakshmi, Yao-Borengasser, Aiwei, Rasouli, Neda, Nolen, Greg T., Phanavanh, Bounleut, Starks, Tasha, Gurley, Cathy, Simpson, Pippa, McGehee, Robert E., Kern, Philip A., Peterson, Charlotte A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692398/
https://ncbi.nlm.nih.gov/pubmed/19336660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.90885.2008
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