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Transcriptome-Wide Mapping of 5-methylcytidine RNA Modifications in Bacteria, Archaea, and Yeast Reveals m(5)C within Archaeal mRNAs

The presence of 5-methylcytidine (m(5)C) in tRNA and rRNA molecules of a wide variety of organisms was first observed more than 40 years ago. However, detection of this modification was limited to specific, abundant, RNA species, due to the usage of low-throughput methods. To obtain a high resolutio...

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Main Authors: Edelheit, Sarit, Schwartz, Schraga, Mumbach, Maxwell R., Wurtzel, Omri, Sorek, Rotem
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3694839/
https://ncbi.nlm.nih.gov/pubmed/23825970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003602
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