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The Identification of Trans-acting Factors That Regulate the Expression of GDF5 via the Osteoarthritis Susceptibility SNP rs143383

rs143383 is a C to T transition SNP located in the 5′untranslated region (5′UTR) of the growth differentiation factor 5 gene GDF5. The T allele of the SNP is associated with increased risk of osteoarthritis (OA) in Europeans and in Asians. This susceptibility is mediated by the T allele producing le...

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Bibliographische Detailangaben
Hauptverfasser: Syddall, Catherine M., Reynard, Louise N., Young, David A., Loughlin, John
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3694828/
https://ncbi.nlm.nih.gov/pubmed/23825960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003557
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