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Functional characterisation of the osteoarthritis susceptibility locus at chromosome 6q14.1 marked by the polymorphism rs9350591

BACKGROUND: The arcOGEN genome-wide association study reported the rs9350591 C/T single nucleotide polymorphism (SNP) as marking a region on chromosome 6q14.1 that is associated with hip osteoarthritis (OA) in Europeans, with an odds ratio (OR) of 1.18 and a p-value of 2.42 × 10(−9). rs9350591 is an...

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Pubblicato in:BMC Med Genet
Autori principali: Johnson, Katherine, Reynard, Louise N., Loughlin, John
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4562116/
https://ncbi.nlm.nih.gov/pubmed/26346884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12881-015-0215-9
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