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The zinc finger protein GLI transforms primary cells in cooperation with adenovirus E1A.

The GLI gene was previously isolated by virtue of its amplification in human glioblastomas. We have now found that GLI expression can result in the in vitro transformation of both primary and secondary rodent cells. When coexpressed with adenovirus E1A, the GLI protein functions analogously to RAS,...

詳細記述

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書誌詳細
出版年:Mol Cell Biol
主要な著者: Ruppert, J M, Vogelstein, B, Kinzler, K W
フォーマット: Artigo
言語:Inglês
出版事項: Taylor & Francis 1991
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369482/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1825351/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.3.1724-1728.1991
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