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Predominance of activated, clonally expanded T helper type 17 cells within the CD4(+) T cell population in psoriatic lesions
Recent evidence points to the T helper type 17 (Th17) subset as key in the pathogenesis of psoriasis, but cells of this type in lesions remain to be fully characterized. Here we isolated, enumerated, functionally tested and clonotyped the CD4(+) Th cell population ex vivo from lesional biopsies and...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Blackwell Science Inc
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3694533/ https://ncbi.nlm.nih.gov/pubmed/23607572 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12086 |
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