A Biochemical Screen for Identification of Small-Molecule Regulators of the Wnt Pathway Using Xenopus Egg Extracts

Misregulation of the Wnt pathway has been shown to be responsible for a variety of human diseases, most notably cancers. Screens for inhibitors of this pathway have been performed almost exclusively using cultured mammalian cells or with purified proteins. We have previously developed a biochemical...

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Auteurs principaux: Thorne, Curtis A., Lafleur, Bonnie, Lewis, Michelle, Hanson, Alison J., Jernigan, Kristin K., Weaver, David C., Huppert, Kari A., Chen, Tony W., Wichadiit, Chonlarat, Cselenyi, Christopher S., Tahinci, Emilios, Meyers, Kelly C., Waskow, Emily, Orton, Darren, Salic, Adrian, Lee, Laura A., Robbins, David J., Huppert, Stacey S., Lee, Ethan
Format: Artigo
Langue:Inglês
Publié: 2011
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3694444/
https://ncbi.nlm.nih.gov/pubmed/21859680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057111416657
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