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α-Synuclein mutations cluster around a putative protein loop()
With the recent identification of two new pathogenic mutations in α-synuclein, we map the five known pathogenic mutations onto the best available models of the protein structure. We show that four of the five mutations map to a potential fold in the protein with the exception being the A30P mutation...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier Scientific Publishers Ireland
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3694303/ https://ncbi.nlm.nih.gov/pubmed/23669636 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2013.04.058 |
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