Cytotoxic T Lymphocytes Derived from Patients with Chronic Hepatitis C Virus Infection Kill Bystander Cells via Fas-FasL Interaction

The role of Fas-mediated lysis of hepatocytes in hepatitis C virus (HCV)-induced injury is frequently discussed. We therefore analyzed the effect of the number of HCV antigen-expressing cells, the mode of antigen presentation, and the number of cytotoxic T lymphocytes in a coculture system mimicking...

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Autores principales: Gremion, Christel, Grabscheid, Benno, Wölk, Benno, Moradpour, Darius, Reichen, Jürg, Pichler, Werner, Cerny, Andreas
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2004
Materias:
Pathogenesis and Immunity
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC369426/
https://ncbi.nlm.nih.gov/pubmed/14747581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.4.2152-2157.2004
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