Primary breast cancer stem-like cells metastasise to bone, switch phenotype and acquire a bone tropism signature

BACKGROUND: Bone metastases represent a common and severe complication in breast cancer, and the involvement of cancer stem cells (CSCs) in the promotion of bone metastasis is currently under discussion. Here, we used a human-in-mice model to study bone metastasis formation due to primary breast CSC...

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Detalhes bibliográficos
Main Authors: D′Amico, L, Patanè, S, Grange, C, Bussolati, B, Isella, C, Fontani, L, Godio, L, Cilli, M, D′Amelio, P, Isaia, G, Medico, E, Ferracini, R, Roato, I
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3694250/
https://ncbi.nlm.nih.gov/pubmed/23801032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.271
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